비밀번호 확인 :
Prof. Chankyu Park’s Team Discovers Hair Length Regulating Genes of Sapsaree Dogs
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2022.01.04
<p> <span style="color: #333333; font-family: arial,helvetica,sans-serif;"><span style="font-size: 11pt;"><img width="324" height="410" style="margin-right: 10px; margin-left: 10px; float: left;" src="ArticleFile.do?id=11836595" /></span><span style="font-size: 11pt;"><span style="font-size: 10pt;">Prof. Chankyu Park’s research team from Konkuk University’s Konkuk Institute of Science and Technology (KIT) (Department of Stem Cell and Regenerative Biotechnology) announced on the 3<sup>rd</sup> that they have identified a gene causing the change in hair length of Korean native dog, Sapsaree dog, which is designated as natural monuments in Korea, and the mechanism of long and short hair dogs. (Thesis title: Tracing the origin of the RSPO2 long hair allele and epistatic interaction between FGF5 and RSPO2 in Sapsaree dog)<br /><br /><span style="color: #333333; font-family: arial,helvetica,sans-serif; font-size: 10pt;"><span><span style="color: #333333; font-family: arial,helvetica,sans-serif; font-size: 10pt;"><span>According to the research team, this finding provided significant data about the history of dog breeds around the world proving that all long hair dog breeds share same type of mutant RSPO2 gene. The team has also developed a gene testing technology that can predict the long breed and rare short breed of Sapsaree dog.<br /><br /><span style="color: #333333; font-family: arial,helvetica,sans-serif; font-size: 10pt;"><span><span style="color: #333333; font-family: arial,helvetica,sans-serif; font-size: 10pt;"><span>Prof. Park said, “This research will contribute to the understanding of Korean native dogs using the genome information, preservation and development of international awareness of Korean native dogs, and biological understanding of pets.”<br /><br /><span style="color: #333333; font-family: arial,helvetica,sans-serif; font-size: 10pt;"><span><span style="color: #333333; font-family: arial,helvetica,sans-serif; font-size: 10pt;"><span>Supported by the Rural Development Administration, the research was jointly conducted with the Korean Sapsaree Foundation, affiliated with the Center for Companion Animal Research, and Yeungnam University. The research results (first author: Ph.D. Minkyu Kang/Byungyong Ahn) was published in the online edition of Genes, an international renowned journal in molecular genetics, on January 1<sup>st</sup>. The long and short hair Sapsaree dogs were recently registered as a natural monument by the Cultural Heritage Administration.</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></p> <p><span style="font-size: 11pt;"><br /><br /></span><img width="639" height="245" style="margin-right: auto; margin-left: auto; display: block;" alt="" src="ArticleFile.do?id=11836597" /></p> <p style="text-align: center;"><strong><span style="font-family: 한컴산뜻돋움;"><span style="color: #000000; font-size: small;">Image 1. Picture of Sapsaree dog, the natural monument. The difference between long hair and short hair Sapsaree dog is caused by mutant type of RSPO2. (Pictures provided by the Korean Sapsaree Foundation)<span style="font-size: 11pt;"><br /><img width="656" height="453" style="margin-right: auto; margin-left: auto; display: block;" alt="" src="ArticleFile.do?id=11836596" /></span><strong><br /><span style="font-family: 한컴산뜻돋움;"><span style="color: #000000; font-size: small;">Image 2. Using the multi-dimensional scale method, hair length phenotypes of all short and long hair dogs around the world are classified according to genetic information. The long hair breeds colored with blue form a cluster on the right.<strong><span style="font-family: 한컴산뜻돋움;"><span style="color: #000000; font-size: small;"><strong><br /></strong></span></span></strong></span></span></strong></span></span></strong></p>
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