비밀번호 확인 :
KU Professor Generates Gene Integration-free iPSCs
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2016.06.30
<p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;">On June 28, 2016, Konkuk University announced that Professor Ssang-Goo Cho’s research team generated gene integration-free induced pluripotent stem cells (iPSCs) with technology employing graphene oxide-polyethylenimine (GO-PEI) complexes. Production of such iPSCs is required to avoid the potential risk of insertional mutagenesis during clinical applications. In collaboration with Professor Byung-Soo Kim of Seoul National University’s Department of Chemical and Biological Engineering, the research team reported an mRNA delivery system using GO-PEI complexes that can effectively load mRNA of reprogramming transcription factors and offer protection from mRNA degradation. The results were published in the Journal of Controlled Release in an article titled “Efficient mRNA Delivery with GO-PEI for Generation of Footprint-free Human Induced Pluripotent Stem Cells.”</span></p> <p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;"> <img style="margin-left: auto; display: block; margin-right: auto;" alt="" src="ArticleFile.do?id=11665683" /></span></p>
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