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KU Research Team Develops Highly Efficient Technology to Generate Induced Hepatocyte-like Cells
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819
2016.04.18
<p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;">A KU research team identified a direct conversion mechanism to reduce the reduce the time required for induced hepatocyte-like cells (iHeps) generation, increasing efficiency by up to 90 times. By overcoming the limitations to the existing direct conversion technologies, the research is expected to be used in treating hard-to-cure liver diseases as well as pharmaceutical applications. It was led by Professor Dong Wook Han of KU’s School of Medicine and conducted by Mr. Kyung Tae Lim, a Ph.D. student. The research received funding from the Rural Development Administration’s Next-Generation BioGreen21 program as well as the National Research Foundation of Korea’s Basic Science Research program and the Bio & Medical Technology Development program. The results were published in an article titled “Small Molecules Facilitate Single Factor-mediated Hepatic Reprogramming” on the online version of <em>Cell Reports</em> by the peer-reviewed scientific journal <em>Cell</em> in April 2016.</span></p> <p><img style="margin-left: auto; display: block; margin-right: auto;" alt="" src="ArticleFile.do?id=11658013" /><br /><br /></p> <p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;"> </span></p>
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