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Konkuk Professor Studies Reasons for Ineffectiveness of IFN Therapy for HBV Infections
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757
2017.04.06
<p><img style="margin-left: auto; display: block; margin-right: auto;" alt="" src="ArticleFile.do?id=11692113" /><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;">A Konkuk research team led by Professor Kyun-Hwan Kim of the Department of Pharmacology and Center for Cancer Research and Diagnostic Medicine Kim studied why interferons therapy for HBV infection is less effective than for other viral infections using a mouse model, primary human hepatocytes, and human liver tissues. The results elucidated a mechanism by which HBV evades the host innate immune system.</span></p> <p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;">The study was published in Gut on March 23 in an article titled “Suppression of interferon-mediated anti-HBV response by single CpG methylation in the 5′-UTR of <em>TRIM22”</em> with Dr. Keo-Heun Lim listed as the first author. The research was supported by a National Research Foundation grant and the Korea Health Technology R&D Project through the Korea Health Industry Development Institute, funded by the Ministry of Health and Welfare.</span></p> <p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;"> </span></p> <p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;"> </span></p>
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Konkuk Professor Co-Authors F...
Konkuk Research Team Develops...