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Professor Jeong Tae Do’s Research Team Establishes a Dual Reporter System to Distinguish Naive and Primed Pluripotency
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2016.11.09
<p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;"><img style="margin-left: auto; display: block; margin-right: auto;" alt="" src="ArticleFile.do?id=11677387" /><br />On November 8, 2016, Konkuk University announced that Professor Jeong Tae Do’s research team published an article titled “Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency” in Stem Cell Reports. Pluripotent cells are able to self-renew and can potentially differentiate into somatic cells. Inner cell mass of blastocyst form naive pluripotent stem cells, whereas epiblast cells from primed pluripotent stem cells. While they share many important markers, the latter is limited in terms of differentiation potential in vivo. The research team used Oct4, a commonly expressed gene in such sells, to establish a dual reporter system with two fluorescent reporters to distinguish the two. The research was supported by a National Research Foundation of Korea grant by the Ministry of Science, ICT and Future Planning as well as the Next-Generation BioGreen21 Program funded by the Rural Development Administration.</span></p> <p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;"> </span></p> <p><span style="font-size: 10pt; font-family: arial, helvetica, sans-serif;"> </span></p>
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