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Research Team Led by Prof. Roger Kornberg Wins a 19M USD Project
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2014.03.25
<p>Prof. Roger Kornberg, Nobel Laureate in Chemistry (2006) and University Professor of Konkuk University (KU), and his research team including the KU Global Laboratory have won a new drug development research grant from China with a project budget of about 19 million USD. The grant is named "The 3<sup>rd</sup> Introduced Innovative R&D Team Leadership of Guangdong Province" and will be conducted for the next five years. With Dr. Kornberg as the principal investigator, the research team consists of five sub-principal investigators: Dr. Lin-Woo Kang (KU and KU Global Lab, Korea), Dr. Young-Joon Kim (Yonsei University, Korea), Dr. Yuichiro Takagi (Indiana University, US), Dr. Zhong Wang (Sun Yat-sen University), and Dr. Qing Li (Sun Yat-sen University). The project involves Sun Yat-sen University, a top-tier university in China with excellent programs and achievements in chemosynthesis and toxicology.</p> <p>It is unprecedented for the three nations - Korea, China, and the US - to win a large-scale research fund to investigate new medicine with the participation of eminent international scholars and a top global biopharmaceutical company, Cocrystal Discovery Inc. (US). This research on new drug development based on target protein structures is expected to contribute greatly to the fields of science and technology as well as the commercialization of new drugs.</p> <p>Prof. Kornberg is also participating in the "Structural Proteomics Research on Protein Complex that is Involved in Transcription" conducted by Prof. Ye Sun Han's team at KU. Moreover, since 2007, Dr. Kornberg has been working on the "Structural Proteomics Research of <em>Xanthomonas oryzae pv. oryzae</em> causing Bacterial Leaf Blight in Rice" funded by the Rural Development Administration (Korea) with Prof. Lin-Woo Kang (KU). Based on the tens of target protein structures determined by X-ray crystallography thus far, novel small compounds that inhibit the targets have been systematically searched.</p> <p>Prof. Kornberg's such previous research contributions have revealed the basic eukaryotic transcription mechanism by the determination of the megadalton multiprotein transcription machinery at atomic resolution; thus, paving the way for winning this research grant.</p> <p> <img src="ArticleFile.do?id=11587634" /></p> <p> </p> <p style="text-align: right;">Posted by Eun Jin Cho</p>
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