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Research Team at KU Signals Hope for Transplantation Biology
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2014.11.07
<p>Konkuk University's (KU) research team succeeded in producing the first animal with severe combined immune deficiency (SCID) phenotype and lacking T and B cells. Supported by the Woo Jang-Choon project (Head: Prof. Jin Hoi Kim; KU) and the Next-Generation BioGreen 21 Program (Head: Prof. Nam-Hyung Kim; Chungbuk National University) of Korea's Rural Development Administration (RDA), researchers at KU and the University of Missouri jointly produced the cloned pig.</p> <p style="text-align: center;"><img src="ArticleFile.do?id=11607129" /></p> <p style="text-align: center;">Photo: Prof. Jin Hoi Kim (left) and Prof. Deug-Nam Kwon (right)</p> <p style="text-align: center;">of Dept. of Animal Biotechnology, KU College of Animal Bioscience & Technology</p> <p style="text-align: center;"> </p> <p>The research outcomes were published online on May 6, 2014, in the Proceedings of the National Academy of Sciences (PNAS; IF: 9.7), titled "Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency."</p> <p><img width="700" src="ArticleFile.do?id=11607130" /></p> <p>The research results are expected to be applied as a useful tool for stem cell treatment, xenotransplantation of animal organs for patients with incurable diseases, treatment of AIDS and other immunodeficiency disorders, and the investigation of cancer development mechanisms. Since 2002 when he produced Korea's first cloned pig, Prof. Kim has been playing an active role as a global leader in the field of biomedicine and organ transplantation by developing various transgenic pigs.</p> <p> </p> <p style="text-align: right;">Posted by Eun Jin Cho</p>
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